Methanol-free MCDh Haematology Stain

RAL Diagnostics MCDh Reagent

MCDh (Micro Chromatic Detection for Haematology) is a panoptic haematology staining method. Methanol-free, it is made of a sequence of four specific reagents used in blood and bone marrow cell differentiation and counting. This new generation of stains is in line with the standardisation trend in diagnostic techniques.

Revolutionary features

  • Ready to use: unlike more traditional stains, all MCDh reagents are ready to use, no dilution needed, consistency and standardisation are therefore guarantee
  • Methanol-free: MCDh reagents ensure higher safety for user
  • Fast: within only 10 minutes versus 20 minutes for standard stainings, MCDh gives sharper results
  • Polyvalent: MCDh reagents fit both manual and automatic staining techniques
  • Clean: easily rinsed, MCDh reagents facilitate cleaning of staining jars and maintenance of automated instruments
  • Digital Quality: thanks to its standardised consistency, MCDh staining is the best choice for computer aided image recognition

Technical Features

Ethanol-based, MCDh 1 is a blend of neutral stains used as a fixation and set-up solution, particularly for the water-soluble elements (basophilic granules). These stains are not active in alcoholic media and only act selectively when released into MCDh 2. This leads to the precipitation of stains in erythrocytes, eosinophil granules and neutrophil leukocyte cytoplasma. MCDh 3 is used for monocyte and lymphocyte cytoplasm staining and red metachromatic staining of azurophil granules. MCDh 4 will remove excess stain and complete the staining.

Standard Procedure for MCDh Blood Smear

MCDh Haematology staining process flow


RAL MCDh Specification Sheet

RAL MCDh Instructions for Use

Reagent Size Product Code
MCDh 1 1ℓ / 2.5ℓ CB313590 - 1000/2500
MCDh 2 1ℓ / 2.5ℓ CB313570 - 1000/2500
MCDh 3 1ℓ / 2.5ℓ CB313560 - 1000/2500
MCDh 4 1ℓ / 2.5ℓ CB313600 - 1000/2500