Product Information

recomLine Campylobacter IgG   CB37/6272

recomLine Campylobacter IgA   CB37/6273

 

Strip-Immunoassay with antigens produced by recombinant techniques for the detection of IgG and IgA antibodies against Campylobacter jejuni and Campylobacter coli.

 

The genus Campylobacter comprises gram-negative, spiral-shaped, microaerophilic, mesophilic to thermophilic bacteria with bipolar flagella. Human Campylobacter infections are mainly food associated intestinal infections with worldwide incidence. Contaminated and insufficient cooked foods or drinking water in tropical countries are the main sources of infection. The pathogen reservoir is mainly the intestinal tract of warm-blooded wild, domestic and pet animals. Intestinal Campylobacter infections are the second most frequent enteric bacterial infections reported in Germany after enteric Salmonelloses, whereas unreported cases not reflected in the statistics probably outnumber reported cases many times over.

 

Campylobacter jejuni is much more frequent, accounting for over 90% of cases as compared to Campylobacter coli at approx. 9%. Besides nearly asymptomatic (clinically inapparent) courses, infected persons suffer from painful gastrointestinal symptoms with sometimes bloody diarrhoea, fever, meningism and myalgias. In rare cases sequelae like post infectious Reactive Arthritis or Guillain-Barré Syndrome may develop with onset a few weeks after the primary infection.

 

recomLine Campylobacter is a qualitative in-vitro test for the detection of IgG and IgA antibodies against immunodominant antigens of Campylobacter jejuni and Campylobacter coli. In cases of previous or persistent Campylobacter infection with primary diagnosis based on stool sample culturing, recomLine Campylobacter provides for identification of specific Campylobacter antibodies by means of separate line-ups of different antigens produced by recombinant engineering for the purpose of clarifying post infection complications