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Product Information

 

recomBlot BorreliaNB IgG  CB37/4202

recomBlot BorreliaNB IgM   CB37/4203

 

Immunoblot test with antigens produced by recombinant techniques for the detection of IgG or IgM antibodies directed against Borrelia burgdorferi.

 

The bacterium Borrelia burgdorferi, a spirochete, is responsible for Lyme borreliosis. This disease is transmitted to humans by ticks. Lyme borreliosis is a multisystemic disease with diverse manifestations, which make clinical diagnosis difficult. Direct detection of the pathogen is also problematic. Therefore, in routine diagnosis, the serological detection of Borrelia-specific antibodies represents the easiest and safest method for the detection of a Borrelia infection.

 

Enzyme immunoassays or immunofluorescence assays are mainly used for screening. In comparison with the screening assays, recomBlot BorreliaNB exhibits additional criteria with regard to sensitivity and specificity. It allows the detection and identification of IgM and IgG antibodies and is used to confirm the results of the indirect immunofluorescence and enzyme immunoassays. The application of highly specific and immunodominant Borrelia proteins is made possible by the use of antigens produced by genetic engineering.

 

Only the recomBlot BorreliaNB detects antibodies against all three genospecies (Borrelia burgdorferi sensu stricto, Borrelia garinii and Borrelia afzelii) on one single test strip:

 

 

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